Influences of Other Diseases on Cataract and Refractive Conditions

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Refractive errors are very common nowadays but some people having certain disorders are more prone to these refractive conditions as compared to normal people. These disorders are known as increased risk conditions. Cataracts may be hereditary or secondary to a noxious intrauterine event (e.g., rubella). Cataracts associated with a systemic or genetic illness may not occur until the second or third decade (e.g., cataracts associated with retinitis pigmentosa). Even age-related cataracts, generally thought to be due to multiple insults accumulated over many years, have a genetic component, making certain individuals more vulnerable to the environmental insults. It seems likely that when mutations in crystalline or other lens proteins are sufficient in and of themselves to cause protein aggregation they usually result in congenital cataract, while if they merely increase susceptibility to environmental insults, such as light, hyperglycaemic, or oxidative damage, they might contribute to age-related cataract.

Genetic Illnesses of Cataract
Myotonic Dystrophy
Wilson
Homocystinuria and Galactosemia
Autoimmune disorders and Immunodeficiency Conditions
Persistent dry eyes andf Unstable Vision
Keratoconus and Keratitis
Uveitis and Herpes Simplex

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